Hikontsil

Hikontsil – the semi-synthetic antibiotic penicillin applied to treatment of a wide range of diseases.

Pharmacological action

Active component of Hikontsil possesses a wide range of bactericidal action that allows to use it for treatment of many diseases. As a result of Hikontsil's use the synthesis of a peptidoglikan happening during division and growth that involves death of bacteria is broken.

Release form

Hikontsil release in a look:

• Capsules with the content of active agent in number of 250 and 500 mg;
• Powder for preparation of suspension for intake in which 5 ml 125 and 250 mg of active agent contain.

Hikontsil's analogs are the following medicines:

• On active agent – Amoxicillin, Ospamoks, Ekobol, Amosin and Gramoks-D;
• On a way of action – Ampitsillin, Standatsillin, Ampitsillin-Fereyn.

Indications to Hikontsil's use

According to the instruction Hikontsil appoint for treatment of the bacterial infections caused by activators, sensitive to medicine, namely:

• Infections of ENT organs – sinusitis, tonsillitis, pharyngitis, acute average otitis;
• Respiratory infections – bronchitis, pneumonia;
• Infections of urinogenital system – a pyelitis, pyelonephritis, an urethritis, cystitis, an endometritis, gonorrhea, a cervicitis;
• Digestive tract infections – dysentery, a salmonellosis, a salmonellezny carriage;
• Infections of soft tissues and skin – impetigo, ugly faces for the second time infected a dermatosis;
• Hay fever;
• Abdominal infections – a cholangitis, peritonitis, cholecystitis;
• Lyme's diseases;
• Listeriosis;
• Sepsis;
• Meningitis.

Besides, Hikontsil is effective for prevention of an endocarditis.

Contraindications

Hikontsil according to the instruction it is contraindicated to apply at hypersensitivity to active or auxiliary components of medicine, and also to other penicillin, karbapenema and cephalosporins. Also Hikontsil do not apply in the period of a lactation.

With care it is necessary to appoint Hikontsil at:

• Polyvalent hypersensitivity to xenobiotics;
• Pregnancies;
• Digestive tract diseases in the anamnesis (especially at the colitis connected using antibiotics);
• Infectious mononucleosis;
• Renal failure.

Hikontsil route of administration

Pill Hikontsil can be taken irrespective of meal:

• Entirely;
• To divide into parts and to chew;
• To part in 20 ml of water (to a condition of syrup);
• To part in 100 ml of water (to a condition of suspension).

To adults and children of 10 years Hikontsil according to the instruction appoint on 0,5 g to three times a day. In cases of a heavy course of an infection the daily dose can be increased twice.

To children Hikontsil appoint in the form of suspension three times a day in the doses corresponding to age.

At premature and newborn children Hikontsil's dosage is reduced or increase time between receptions of a dose. The course of treatment, as a rule, varies from five to twelve days.

At treatment of acute uncomplicated gonorrhea accept once 3 g of Hikontsil, repeated reception of the same dose is recommended to women.

At treatment of paratyphus, a typhoid and other acute infectious diseases of bilious ways and digestive tract, and also at gynecologic infectious diseases appoint 4 tablets of Hikontsil (on 500 mg) three times a day.

Treatment leptospirosis carry out for 6-12 days on 0,5-0,75 g with frequency rate of use four times a day.

At a salmonellonositelstvo treatment longer also makes two-four weeks in a daily dosage of 3-6 g.

After disappearance of clinical signs of a disease treatment by Hikontsil needs to be continued for two-three days.

Against the background of chronic diseases or the lowered resistance of an organism development of superinfection is possible.

For prevention of an endocarditis before carrying out small surgical interventions adult appoint 3-4 g of Hikontsil in 1 hour. If repeated use of Hikontsil is required, the same dose can be accepted in 8-9 hours. The children's dosage usually makes a half of adult.

Against the background of renal failures the interval between Hikontsil's receptions should be increased till 12 o'clock.

At therapy of slight diarrhea by Hikontsil it is recommended to avoid antidiarrheal drugs which reduce an intestines peristaltics.

At Hikontsil's use together with estrogensoderzhashchy oral contraceptives it is whenever possible necessary to use additional methods of contraception.

Side effects of Hikontsil

Hikontsil according to reviews can cause allergic reactions which are most often shown as:

• Dermahemia;
• Rhinitis;
• Small tortoiseshell;
• Quincke's disease;
• Erythematic rashes;
• Conjunctivitis.

It is possible to carry diarrhea, taste change, vomiting, dysbacteriosis, stomatitis, nausea, a glossitis to the main disturbances of digestion caused by Hikontsil.

The most probable disturbances of a nervous system are the depression, sleeplessness, confusion of consciousness, dizziness, excitement, uneasiness, change of behavior, a peripheral neuropathy, an ataxy and epileptic reactions.

Much less often Hikontsil according to reviews causes:

• Arthralgia;
• Fever;
• Exfoliative dermatitis;
• Eosinophilia;
• Pseudomembranous coloenteritis;
• Multiformny exudative erythema.

Besides, at Hikontsil's use according to reviews can develop:

• Anemia;
• Intersticial nephrite;
• Leukopenia;
• The complicated breath;
• Neutropenia;
• Vagina candidiasis;
• Werlhof's disease;
• Tachycardia.

At reception of high doses of Hikontsil the following symptoms of overdose can be shown:

• Nausea;
• Vomiting;
• Disturbance of water and electrolytic balance;
• Diarrhea.

Medicinal interaction of Hikontsil

Hikontsil it is not necessary to apply along with some medicines in order to avoid development of undesirable side effects and change of therapeutic effect. So, Hikontsil pharmaceutical is incompatible with aminoglycosides owing to what they cannot be mixed.

Hikontsil's absorption according to the instruction:

• Slow down – a glycosamine, antacids, laxative drugs and aminoglycosides;
• Raises – ascorbic acid.

Bactericidal antibiotics, including aminoglycosides, Vancomycinum, cephalosporins and rifampicin have Sinergidny effect.

Such bacteriostatic medicines as chloramphenicol, macroleads, tetracyclines, linkozamida and streptocides have antagonistic effect.

Besides, at simultaneous use with other drugs it is necessary to consider that:

• Hikontsil increases efficiency of indirect anticoagulants;
• Concentration of active components of Hikontsil in blood is increased: Allopyrinolum, diuretics, phenylbutazone, оксифенбутазон and other drugs which block canalicular secretion;
• The risk of development of skin rash raises Allopyrinolum.

Storage conditions

Hikontsil treats a number of antibiotic medicines of a prescription issue with a period of storage up to three years.